Lazarov, Orly PHD

University of Illinois, Chicago

INCLUDE Grants

The role of APP in neurogenesis and AD in Down syndrome

Grant Number RF1AG079002

NIH Institute NIA

Mechanism RF1

Lazarov, Orly

This project examines the role of amyloid precursor protein overexpression in cortical malformation and Alzheimer’s disease in Down syndrome using induced pluripotent stem cells of Down syndrome that were edited to eliminate one APP allele.

Want to stay in touch?

Subscribe to our newsletters and updates.

"*" indicates required fields

Δ

Facebook

This field is for validation purposes and should be left unchanged.

Email*

Privacy Policy

Designed by Digital Silk

The INCLUDE Data Coordinating Center (DCC) is supported by the National Institutes of Health INCLUDE Project under Project Number U2CHL156291 administered by the National Heart, Lung and Blood Institute. All content, terms and conditions and policies associated with the INCLUDE DCC content and website (the “Services”) are produced by the INCLUDE DCC. The views and opinions of authors expressed on the Services do not necessarily state or reflect those of the National Institutes of Health (“NIH”) or the U.S. government. Furthermore, the NIH does not endorse or promote any INCLUDE DCC entity or any of its products or services nor guarantees the products, services, or information provided by the INCLUDE DCC.