Researchers
MUNSHI, NIKHIL VILAS
Ut Southwestern Medical Center
INCLUDE Grants
CRISPR interference to identify HSA21 genes reducing neurogenesis
Grant Number
R21HD118402
NIH Institute
NICHD
Mechanism
R21
Project Narrative
The goal of this proposal is to develop a genetic screen in single cells with selectable markers that can be used
for high through-put, unbiased identification of genes, or combinations of genes, on human chromosome 21 that
contribute to Down syndrome pathologies at the earliest stages of development.