Down syndrome and Psoriasis: An Investigation of Cardiometabolic Risk

This project is a novel study of psoriasis in individuals with Down syndrome (DS). Psoriasis is associated with increased cardiometabolic risk factors and cardiovascular disease in the general population; however, this association has never been explored in people with DS who are considered protected against cardiovascular disease. This study will use a population-level database to enhance our understanding of psoriasis in people with DS and explore if psoriasis could present an exception to their presumed cardiovascular disease resilience.