THURMAN, ANGELA JOHN PHD

Project Narrative Despite the ubiquitous nature of EC delays in Down syndrome (DS), significant variability is observed across children in the nature of these delays. Most EC research approaches in DS have used research designs that mask within-group variability and cannot identify subtypes based on their developmental trajectories, hampering the implementation of individualized treatment options. We propose a three-year longitudinal investigation of EC development, using a multi-method, dense sampling approach that will allow us to significantly improve our ability to monitor EC progress over time in children with DS and improve our prediction of developmental patterns, thereby enabling the future creation of personalized pathways for early assessment and intervention.