Emergence and Stability of Autism in Fragile X Syndrome

Autism is a Devastating and Common Developmental Disorder that is a Major Public Health Concern. Fragile X syndrome is the leading known genetic cause of autism, and both FXS and the FMR1 premutation are highly associated with autism. There is considerable interest in studying the association of FX-disorders contrasted to idiopathic autism spectrum disorder due to the clinical consequences of their co-occurrence in FX and implications for increased understanding of ASD.