INCLUDE19-Ancestral roles of histone-modifying genes in heart development and disease

Han, Zhe

Summary

This project is an addition to an ongoing study using Drosophila to model Congenital Heart Disease (CHD). The added part is to use the powerful genetic tools in Drosophila to identify gene combinations that cause CHD in Down Syndrome (DS) patients, and to investigate the molecular mechanism of CHD in DS.

Grant Number

3R01HL134940-03S1

NIH Institute

NHLBI

Mechanism

R01

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