Researchers
Dierssen, Mara PhD
Centre for Genomic Regulation
INCLUDE Grants
Molecular regulators of GABAergic systems that underlie comorbidities in Down syndrome
Grant Number
R01NS137222
NIH Institute
NINDS
Mechanism
R01
The proposed research is relevant to public health because it will identify molecular regulators that underlie comorbidities in Down syndrome, which will offer insights into the development of therapeutic treatments that target these conditions. It will also provide molecular and cellular insights into other neurological disorders, such as intellectual disabilities, epilepsy, and ASD. Thus, the proposed research is relevant to NIH’s mission because it is expected to develop fundamental knowledge that will help to reduce the burdens of disease and disability.
Publications
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Neuromolecular medicine
Imagine, Discover, Inspire: Proceedings of the 4th International Conference of the Trisomy 21 Research Society. -
Journal of global health
Differences in clinical presentation, severity, and treatment of COVID-19 among individuals with Down syndrome from India and high-income countries: Data from the Trisomy 21 Research Society survey.