Researchers
Sheltzer, Jason PHD
Federation of American Societies for Experimental Biology
INCLUDE Grants
FASEB SRC: The Consequences of Aneuploidy: Honoring the Contributions of Angelika Amon
Grant Number
R13CA271716
NIH Institute
NCI
Mechanism
R13
We are requesting R13 grant funding for a conference entitled, “The Consequences of Aneuploidy: Honoring the Contributions of Angelika Amon.” The conference will be held from September 11th to 16th, 2022, in Southbridge, Massachusetts, and will be sponsored by the Federation of American Societies for Experimental Biology (FASEB). The conference will highlight recent advances in the fast-moving field of aneuploidy biology, and it will memorialize Angelika Amon, a leader in this field who passed away from ovarian cancer in 2020.
Genomic and functional approaches to characterize Chr1q gains in cancer
Grant Number
3R01CA276666-02S1
NIH Institute
NCI
Mechanism
R01
Approximately 25% of human tumors harbor a gain of the “q” arm of chromosome 1, but the functional consequences of this large-scale dosage change are unknown. We will develop and employ novel computational and genetic strategies to characterize the functional consequences of this alteration. These studies will shed light on the physiological effects of a ubiquitous but poorly-understood feature of tumor genomes.