Researchers
Han, Zhe PHD
Children's National Medical Center
INCLUDE Grants
INCLUDE19-Ancestral roles of histone-modifying genes in heart development and disease
Grant Number
3R01HL134940-03S1
NIH Institute
NHLBI
Mechanism
R01
This project is an addition to an ongoing study using Drosophila to model Congenital Heart Disease (CHD). The added part is to use the powerful genetic tools in Drosophila to identify gene combinations that cause CHD in Down Syndrome (DS) patients, and to investigate the molecular mechanism of CHD in DS.